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產(chǎn)品中心抗體/抗原流式抗體S0B5103Rat Anti-Mouse CD170 Antibody (S-R691)
產(chǎn)品型號：S0B5103
更新時間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：73
服務熱線15855403091
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相關文章
CD170, also known as Siglec-5 or OBBP2, is a type I transmembrane glycoprotein and a member of the sialic acid-binding Ig-like lectin （Siglec） family. It is expressed on various immune cells, including monocytes, neutrophils, macrophages, and dendritic cells. This molecule is characterized by its ability to bind sialic acids, which are often found on the surface of cells. It contains an immunoreceptor tyrosine-based inhibitory motif （ITIM） in its cytoplasmic domain, which is involved in intracellular signaling and can inhibit the activation of immune cells. CD170 is involved in mediating sialic acid-dependent cell adhesion and plays a role in immune regulation. In addition, it has been implicated in immune evasion by certain pathogens, such as Group B Streptococcus.
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