PE Mouse Anti-Human CD42b Antibody (S-935-7)

產(chǎn)品型號(hào)：S0B5158

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD42b, also known as platelet glycoprotein Ib alpha chain （GPIbα）, is a type I transmembrane glycoprotein with a molecular weight of approximately 145 kDa. It is encoded by the GP1BA gene and primarily expressed on the surface of platelets and megakaryocytes. CD42b forms a complex with other proteins, including CD42c （GPIbβ）, CD42a （GPIX）, and CD42d （GPV）, which is essential for platelet adhesion and aggregation. This complex plays a crucial role in hemostasis by binding to von Willebrand factor （vWF）, facilitating platelet attachment to the subendothelium at sites of vascular injury. Mutations or deficiencies in CD42b are associated with Bernard-Soulier syndrome, a rare bleeding disorder characterized by large platelets and impaired platelet function.

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