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產(chǎn)品中心抗體/抗原流式抗體S0B5179Rat Anti-Mouse CD182 Antibody (S-R718)
產(chǎn)品型號：S0B5179
更新時間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：116
服務(wù)熱線15855403091
產(chǎn)品分類
CD182, also known as CXCR2 or IL-8 receptor beta, is a 67-70 kDa member of the G-protein-coupled receptor family with seven transmembrane regions. It is expressed on various cell types, including neutrophils, natural killer cells, T cell subsets, monocytes, endothelial cells, and others. CD182 plays a crucial role in mediating chemotaxis, cell activation, proliferation, and angiogenesis. It binds to chemokines such as IL-8, NAP-2, GCP-2, and GRO-alpha, -beta, and -gamma, which induce these biological effects. This receptor is also involved in neutrophil migration to sites of inflammation and is essential for the positioning of oligodendrocyte precursors in the developing spinal cord.
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